COMPLEMENT FACTOR H-RELATED PROTEINS CFHR2 AND CFHR5 REPRESENT NOVEL LIGANDS FOR THE INFECTION-ASSOCIATED CRASP PROTEINS OF BORRELIA BURGDORFERI.

Complement factor H-related proteins CFHR2 and CFHR5 represent novel ligands for the infection-associated CRASP proteins of Borrelia burgdorferi.

One virulence property of Borrelia burgdorferi is its resistance to innate immunity, in particular to complement-mediated killing.Serum-resistant B.burgdorferi express up to five distinct complement regulator-acquiring surface proteins (CRASP) which interact with complement regulator factor H (CFH) and factor H-like protein 1 (FHL1) or factor H-rel

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A clinical case of a patient with an anomaly in the development of the inner ear and refractory stimulation of the facial nerve after a coronavirus infection and meningitis

Background.Thanks to the development of technology and new surgical approaches, it has become possible to perform cochlear implantation (CI) in patients with malformations of the inner ear.The experience of this type of rehabilitation has more than 15 years in Russian practice and more than 20 years in the world.Unfortunately, the COVID-19 pandemic

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Reproductive toxicity and underlying mechanisms of fine particulate matter (PM2.5) on Caenorhabditis elegans in different seasons

Although numerous studies have investigated that atmospheric fine particulate matter (PM2.5) can be toxic to environmental organisms, the research on the reproductive toxicity of PM2.5 is limited, and the key toxic components and underlying mechanisms remain unknown.In this work, PM2.5 samples of four seasons in Nanjing from March 1, 2021, to Febru

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